Cefim-3 Suspension 50ml

Indications of Cefim-3 50 ml Powder For Suspension

A member of the cephalosporin family of antibiotics, Cefim-3 is used to treat a number of bacterial infections. It works well for infections of the urinary tract, ear, nose, sinuses, throat, and some sexually transmitted diseases. It also works well for infections of the respiratory tract (like pneumonia).

Pharmacology of Cefim-3 50 ml Powder For Suspension

Cefixime is an oral third-generation cephalosporin antibiotic that is semi-synthetic. It is bactericidal against a variety of gram-positive and gram-negative microorganisms at easily attainable plasma concentrations. It kills bacteria by interfering with the synthesis of the bacterial cell wall. It is extremely stable when the enzyme beta-lactamase is present. Because of the presence of beta-lactamases, many organisms that are resistant to penicillins and some cephalosporins may be susceptible to Cefixime. Whether administered with or without meals, it is absorbed 40% to 50% of the time.

Dosage & Administration of Cefim-3 50 ml Powder For Suspension 

The typical treatment period is seven days. Depending on how severe the infection is, this could go on for up to 14 days.

• Adults and children over the age of 12 should take 200–400 mg (1–2 capsules) daily, either all at once or in two divided doses. Cefixime 400 mg is prescribed orally once for the treatment of uncomplicated cervical/urethral gonococcal infections.

Children (at least 6 months old): Usually 8 mg/kg/day administered as a single dose or in two divided doses, or as follows:

• 1–2 years: 75 mg every day.
• 1-4 years: 100 mg each day.
• 200 mg every day for 5–10 years.
• 11–12 years: daily 300 mg
• The recommended dosage for typhoid fever is 10 mg/kg/day for 14 days.
• Children (under 6 months): Cefixime's safety and effectiveness in children younger than 6 months have not been established.

Interaction of Cefim-3 50 ml Powder For Suspension

Probenecid increases concentrations. Anticoagulants may lengthen the prothrombin time, which could be fatal.

Contraindications of Cefim-3 50 ml Powder For Suspension

Cefixime is an oral third-generation cephalosporin antibiotic that is semi-synthetic. It is bactericidal against a variety of gram-positive and gram-negative microorganisms at easily attained plasma concentrations. It kills bacteria by interfering with the synthesis of the bacterial cell wall. It is extremely stable when the enzyme beta-lactamase is present. Because of the presence of beta-lactamases, many organisms that are resistant to penicillins and some cephalosporins may be susceptible to Cefixime. Whether administered with or without meals, it is absorbed 40% to 50% of the time.

Side Effects of Cefim-3 50 ml Powder For Suspension 

The drug is generally well tolerated. The most frequent side effects, which are more frequently associated with higher dosages, are diarrhea and altered stools. Other side effects include headaches, dizziness, nausea, stomach pain, dyspepsia, vomiting, and flatulence. Allergy symptoms include rashes, pruritus, urticaria, drug fever, and arthralgia. These responses typically subsided when the treatment was discontinued.

Pregnancy & Lactation

However, no appropriate and well-controlled trials in pregnant women have been conducted. Because animal reproduction studies do not always anticipate a human response, this medication should only be taken during pregnancy if absolutely necessary. Cefixime is not known to be excreted in human milk. When Cefixime is given to a breastfeeding mother, care should be used.

Precautions & Warnings

• People with a history of digestive problems, especially colitis, should be advised with caution.
• Care should be taken when giving the medication to patients who have severe renal impairment, are on continuous ambulatory peritoneal dialysis, or are receiving hemodialysis.
• The dosage should only be changed in cases of severe renal failure (creatinine clearance 20 ml/min); in these circumstances, a daily dose of 200 mg should not be exceeded.

Storage Conditions

Keep the temperature below 30°C and keep it away from light and moisture. Keep out of children's reach.